LANCRIX

Macitentan, ≥99%

Catalog No. 040588

Identification
SynonymsACT-064992
CAS No.441798-33-0
M.F.

C19H20Br2N6O4S

M.W.588.27
MDL No.MFCD17167076
Technical Data
AppearanceWhite to off-white crystalline powder
Assay≥99% HPLC
SolubilityDMSO
Storage-20℃
ApplicationMacitentana is an orally active, non-peptide, dual ETA/ETB (endothelin) receptor antagonist with IC50 of 0.5 nM/391 nM.
Safety Data
Reference

Corallo C, et al. J Biol Regul Homeost Agents. 2013 Apr-Jun;27(2):455-62
Bruderer S, et al. Pharmacology. 2013;91(5-6):331-8
Atsmon J, et al. Clin Pharmacokinet. 2013 Aug;52(8):685-92
Weiss J, et al. Eur J Pharmacol. 2013 Feb 15;701(1-3):168-75
Kim SJ, et al. Transl Oncol. 2012 Feb;5(1):39-47

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