CHIR-99021, ≥98%

Catalog No. 586054

General Information

Synonyms	GSK-3 Inhibitor XVI, CHIR 99021
CAS No.	252917-06-9
M.F.	C₂₂H₁₈Cl₂N₈
M.W.	465.34

Technical Data

Appearance	White or light yellow powder
Purity	≥98% HPLC
Solubility	DMSO
Storage	2-8℃
Description	CHIR-99021 is a potent and highly selective inhibitor of glycogen synthase kinase 3 (GSK-3). CHIR-99021 activates glycogen synthesis in CHO-IR cells and in isolated type 1 diabetic rat skeletal muscle. CHIR-99021 has also been shown to induce the reprogramming of murine and human somatic cells into stem cells.

Reference

Van der Jeught M, Stem Cells Dev. 22(2):296-306, (2013)
Lian X, et al. Nat Protoc. 8(1):162-75, (2013)
Moraveji SF, et al. Hum Reprod. 27(8):2312-24, (2012)
Xi J, et al. Stem Cells. 30(8):1655-63, (2012)
Ye S, et al. PLoS One. 7(4):e35892, (2012)
Zhang M, et al. BMC Dev Biol. 12:21, (2012)
Domínguez JM, et al. J Biol Chem. 287(2):893-904, (2012)
Marchand B, et al. Carcinogenesis. 33(3):529-37, (2012)
Lian X, et al. Proc Natl Acad Sci U S A. 109(27):E1848-57, (2012)

Size	Price	Quantity	Favorites
100 mg	USD280
500 mg	USD980
5 g	USD2670

Please inquire for non-standard packs and bulk quantities.

Availability: Ships in 1-3 days

For research use only. Not for human use.

> Certificate of Analysis

> MSDS

	(*Required Field)
*Name
*Organization Name
*Country
*Email Address
Phone
Subject	586054, CHIR-99021, ≥98%, 252917-06-9
*Message
*Code

CHIR-99021, ≥98%

Inquire