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Ceftriaxone disodium salt hemiheptahydrate, ≥98%

Catalog No. 564301

General Information
SynonymsRo-13-9904/001; Rocefin; Rocephine
CAS No.104376-79-6
M.F.

C18H16N8Na2O7S3

·3.5H2O

M.W.661.60
EC No.277-930-0
MDL No.MFCD01750405
PubChem Substance ID24278322
Technical Data
AppearanceWhite or off-white crystalline powder
Specific Rotation (°)-153°~-170°
Purity≥98% HPLC
SolubilitySoluble in Water and Methanol
Storage2-8℃
DescriptionCeftriaxone is a third-generation cephalosporin antibiotic that disrupts the synthesis of the peptidoglycan layer of bacterial cell walls. It is effective against gram-positive and gram-negative bacteria. Ceftriaxone is thought to increase EAAT2 pump expression in the central nervous system and to reduce glutamatergic toxicity.
Safety Data
SymbolGHS08GHS07
Hazard StatementsH315-H317-H319-H334-H335
Precautionary StatementsP261-P280-P305 + P351 + P338-P342 + P311
Hazard SymbolsXn
Risk StatementsR36/37/38-42/43
Safety StatementsS26-36
WGK Germany1
Reference

Reiner, R., et al.: J. Antibiot., 33, 783 (1980)

Patricia A. Arndt and George Garratty Reprod. Sci. 18, 1193-1201, (2011)

Ankica V. Jelenkovic, Marina D. Jovanovic, et al. Exp. Biol. Med. 233, 1389-1394, (2008)

 

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10 g USD525

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