5-Aza-2'-Deoxycytidine, ≥99%

Catalog No. 030807

General Information

Synonyms	2′-Deoxy-5-azacytidine
CAS No.	2353-33-5
M.F.	C₈H₁₂N₄O₄
M.W.	228.21
Beilstein No.	617982
EC No.	219-089-4
MDL No.	MFCD00043011
PubChem Substance ID	24890797

Technical Data

Appearance	White crystalline powder
Assay	≥99%
Solubility	Soluble to 50 mM in water and to 50 mM in DMSO
Storage	Protected from light

Safety Data

Symbol	GHS08 GHS07
Hazard Statements	H302-H315-H319-H335-H341-H360
Precautionary Statements	P201-P261-P281-P305 + P351 + P338-P308 + P313
Hazard Symbols	T
Risk Statements	R61-22-36/37/38-68
Safety Statements	S26-36/37
WGK Germany	3
RTECS	XZ3012000

Reference

Jackson-Grusby et al (1997) Mutagenicity of 5-aza-2'-deoxycytidine is mediated by the mammalian DNA methyltransferase. Proc.Natl.Acad.Sci.USA 94 4681.

Bender et al (1998) Inhibition of DNA methylation by 5-aza-2'-deoxycytidine supresses the growth of human tumour cell lines. Cancer Res. 58 95. PMID: 9426064.

Momparler (2005) Pharmacology of 5-aza-2'-deoxycytidine (decitabine). Semin.Hematol. 42 (Suppl 2) S9. PMID: 16015507.