LANCRIX

Betulinic acid, ≥98%

Catalog No. 484017

Identification
CAS No.472-15-1
M.F.

C30H48O3

M.W.456.70
EC No.207-448-8
MDL No.MFCD00009619
Technical Data
AppearanceWhite or off white powder
Assay≥98% HPLC
SolubilityDMSO
Storage2-8℃, protected from light
ApplicationBetulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism.
Safety Data
Reference

Yunjeong Kim et al Eur. J. Med. Chem. 50, 311-8, (2012)
Mullauer FB, et al. Anticancer. Drugs 22, 223-233, (2011)
Zheng ZW, et al. J. Pharm. Pharmacol. 63, 572-578, (2011)
Li Y, He K, Huang Y, Zheng D, Gao C, et al. Mol. Carcinog. 49, 630-640, (2010)
Dae Sik Jang et al J. Nat. Prod. 68, 1134-6, (2005)
Hiranthi Jayasuriya et al J. Nat. Prod. 68, 1247-52, (2005) 

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