Zofenopril calcium, ≥98.5%

Catalog No. 278082

General Information

Synonyms	Bifril-d5, Zofenil
CAS No.	81938-43-4
M.F.	(C₂₂H₂₂NO₄S₂)₂·Ca
M.W.	897.17
MDL No.	MFCD11858294

Technical Data

Appearance	White or almost white crystalline powder
Specific Rotation (°)	-65° to -70°
Assay	≥98.5%
Solubility	DMSO
Storage	Cool & Dry
Description	Zofenopril is a long-lasting, lipophilic ACE inhibitor. Zofenopril is also an inhibitor of PEPT2, the predominant peptide transporter in kidney and choroid plexus.

Safety Data

Symbol	GHS09
Hazard Statements	H410
Precautionary Statements	P273-P501
Hazard Symbols	N
Risk Statements	R50/53
Safety Statements	S60-61
WGK Germany	3

Reference

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Maurin, C., et al. J. Med. Chem., 47, 5583 (2004)
Marchand, C., et al. Mol. Pharmacol., 64, 600 (2003)
Subissi, A., et al. Cardivascular Drug Reviews, 17, 2 (1999)
Gorren, A., et al. Biochem. J., 331, 801 (1998)
DeForrest, J.M., et al. J. Cardiovasc. Pharmacol. 13, 887-894, (1989)