Triptolide, ≥98%

Catalog No. 557482

General Information

Synonyms	NSC 163062; PG 490
CAS No.	38748-32-2
M.F.	C₂₀H₂₄O₆
M.W.	360.40
MDL No.	MFCD00210565
PubChem Substance ID	24900156
Botanical Source	Tripterygium wilfordii

Technical Data

Appearance	White powder
Melting Point (°C)	226-227˚C
Purity	≥98% HPLC
Solubility	Solube in Methanol, Ethyl acetate, Chloroform, DMSO, etc.
Storage	2-8℃, protected from light
Description	Inhibits cytokine-induced gene expression via inhibition of NF-κB transcriptional activity. Induces apoptosis in tumor cells by blocking TNF-α mediated c-IAP2 and c-IAP1 (members of the inhibitor of apoptosis family) induction. Immunosuppressive with anti-inflammatory and antitumor activity.

Safety Data

WGK Germany	3
RTECS	YK7751000

Reference

Hikim, S., et al.: J. Androl., 21, 431 (2000)

Chang, W.-T., et al.: J. Biol. Chem., 276, 222 (2001)

Kiviharju, T.M., et al.: Clin. Cancer Res., 8, 2666 (2002)

Leuenroth, S.J., et al.: Chem. Biol., 12, 1259 (2005)

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Triptolide, ≥98%

Size	Price	Quantity	Favorites
5 mg	USD98
20 mg	USD160
50 mg	USD225
100 mg	USD290

Please inquire for non-standard packs and bulk quantities.

Availability: Ships in 1-3 days

For research use only. Not for human use.

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